Composite
Part:BBa_K4015009:Design
Designed by: Andrew Peng Yi Group: iGEM21_KEYSTONE (2021-10-19)
CotA-HlyA
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 1348
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 286
Design Notes
Both of them have a secretory function, which leads to the fact that connecting them in one piece hinders the function of both causing the failure to secrete the product.
Source
The parts are assembled by Gibson assembly, and is ligated into pET 23a.